Karina Cervantez INTERVIEW Article Example | Topics and Well Written Essays - 250 words

Karina Cervantez INTERVIEW - Article Example She does this by creating jobs in the area to ensure that people get good pays. According to her, life in California is very expensive. Her other responsibility entails serving in various commission such as the recreation commission where she manages the budgets of the open spaces in the community. She also proposes parks and gardens in the community. She also serves in the planning commission where she addressed land use and housing issues. Moreover, she ensures that people in the city can access the internet in order to improve networking especially among small business persons. One of students asked her to describe her regular day. She said that serving in city council is usually a part time job in their city. She said that each day is different since she performs different tasks. She goes for meetings on the second and fourth Tuesdays of every month where she meets with people to talk about the issues facing the council. On other days she attends community events. She is also a teacher in local colleges. She was also asked about the challenges the council faces. She said that the council faces safety issues especially on roads. Among her challenges include financial problems in the council and less political powers. When asked whether she only served documented individuals in the community, she said that all documented and undocumented access the city services. She said the city’s funds come from the taxations all documented and undocumented

Causes and Effects of Tuberculosis

Causes and Effects of Tuberculosis Tuberculosis is a chronic, infectious and deadly disease caused by Mycobacterium Tuberculosis. Tuberculosis often attacks lungs but it is also known for attacking other parts of the body (extrapulmonary tuberculosis). The infection site of extrapulmonary tuberculosis includes the central nervous system, the lymphatic system particularly in the neck, genitourinary system and bones and joints. People with active tuberculosis often show some of these symptoms: Mycobacteria are found abundantly in habitats such as pond and soil. However, a few are intracellular pathogens to animals and humans. Tuberculosis is transmitted through aerosol route but the transmission can also occur via gastrointestinal route. Coughing, sneezing and spitting by people with active tuberculosis releases droplet nuclei containing the germ which is known as bacilli into the air. The droplet nuclei can remain suspended in the air for up to several hours. Infection only occurs when someone inhales the droplet nuclei. A person needs only to inhale a  treated with existing drugs and medications. To make the condition even worse, new tuberculosis germ (XDR-TB) that is extremely resistant to drugs has been found in US. Now, the governments are focusing more on the preventive measure and at the same time, searching for a possible drug or vaccine that could eliminate the problem once and for all. So, to address this issue, I have focused my research on this question What are current available treatments for tuberculosis? Current Possible Solution With the advancement of technology, mankind had the power in combating with deadly diseases. Tuberculosis, which had killed millions of people in the nineteenth century, was brought under control by using vaccines and drugs. Drug treatments are used extensively in treating people with active tuberculosis. Latent tuberculosis, however, does not require intensive care but merely prescribed medication for several months. Vaccines, on the contrary, are used as preventive measures in areas of higher tuberculosis risk. Apart from that, vaccines are used by healthcare workers, newborns, and travelers who are at constant risk of getting infected by the disease. One of the most commonly used vaccine in prevention of tuberculosis, the BCG vaccine, is discussed below. But, first, I will discuss about the drug treatments. Tuberculosis treated with drugs has a mortality rate of less than 5%. This shows that the current available drugs for tuberculosis are quite effective in treating the disease. Among the common drugs used in tuberculosis treatment are isoniazid, rifampicin, pyrazinamide, and ethambutol. These drugs aim at inhibiting the bacterial activity thus improving the patients conditions. Anti-tuberculosis drugs are classified into three major categories. They are the first line drugs, the second line drugs and the third line drugs. These drugs are classified according to their effectiveness in treating the disease and their availability. The first line drugs are as follows: Ethambutol-EMB or E, Isoniazid-INH or H, Pyrazinamide-PZA or Z, Rifampicin-RMP or R, Streptomycin-STM or S (802 words) There are six classes of second line drugs. These drugs are classified second class because they may be less effective than first line drugs (p-aminosalicylic acid), they may have harmful side-effects (cycloserine) or they may not be available in the developing countries (fluoroquinolones). aminoglycosides: e.g.-amikacin(AMK), kanamycin(KM); polypeptides: e.g.-capreomycin, viomycin, enviomycin; fluoroquinolones: e.g.-ciprofloxacin(CIP), levofloxacin, moxifloxacin(MXF); thioamides: e.g.-ethionamide, prothionamide; cycloserine(the only antibiotic in its class); p-aminosalicylic acid(PAS or P). Other drugs (third line drugs) that may be useful, but are not on the WHO list: rifabutin macrolides: e.g.-clarithromycin(CLR); linezolid(LZD); thioacetazone(T); thioridazine; arginine; vitamin D; R207910. Tuberculosis treatments are often done as combination therapies (except for latent tuberculosis where only one type of drug is prescribed to the patient) because single drug therapy would result in rapid development of resistance which would lead to the failure of the treatment. Besides that, there are other reasons to support the combination therapy. Different drugs have different form of action. For example, PZA is a weak bactericidal but is very effective against bacteria located in acidic conditions. On the other hand, INH is very effective against replicating bacteria. RMP is a good bactericidal and at the same time, has sterilizing effects. This proves that, using combination therapy is effective to counter the disease and at the same time, it would prevent the mutation of the bacteria into drug resistant. Upon infection, tuberculosis bacteria are taken up by the alveolar macrophages and are carried to the lymph nodes where it may be spread to other parts of the body (this is the basis of extrapulmonary tuberculosis). Two to eight weeks after infection, hypersensitivity and cell-mediated immunity develops and suppression of the infection will result in people with good, healthy immune system. People, who are immunocompromised, will develop inflammatory immune response which eventually leads to lung damage. These drugs functions by confining the bacteria and at the same time, since it has antibiotic effects, it will kill the bacteria, thus, improving the patients condition. It would usually take about six months or more for full (1153 words) recovery with 2-3% of relapse rate. Continuation of medication would be recommended by the physician to avoid the problem form reappearing. Isoniazid is one particular type of the drug which is commonly used due to its effectiveness in treating tuberculosis. This medication is best taken on an empty stomach 1 hour before or 2 hours after meals. But it may be taken with food or milk if stomach upset occurs. Take as directed. Do not stop taking this medication without your doctors approval. Stopping therapy early may result in ineffective treatment and the infection could recur. Vitamin B6 (pyridoxine) supplements may be prescribed in addition to this medication to prevent numbness and tingling. Extracted from MedicineNet.com- Isoniazid ORAL (Niazid) side effects, medical uses and drug interaction. Figure 1 Fgure4- Effect of aspirin or ibuprofen administered in combination with isoniazid on lung(a) and spleen(b) log10 CFU in murine tuberculosis. ASP only, aspirin(20 mg/kg of body weight); IBU only, ibuprofen(20 mg/kg); INH only, isoniazid(25 mg/kg); ASP+INH, aspirin and isoniazid(20 and 25 mg/kg, respectively); IBU+INH, ibuprofen and isoniazid(20 and 25 mg/kg, respectively). There is reliable and concrete evidence that isoniazid is effective in curbing the disease. The graph shows clearly that when isoniazid is administered to a patient with murine tuberculosis, it effectively inhibits the progress of the disease. This can be seen when there is zero tuberculous bacterium count when INH is administered. The drug acts in the same way in both liver and spleen. Other drugs, such as ibuprofen and aspirin are used to compare the relative effectiveness of each individual drug. Ibuprofen seems not to interfere with the INH mechanism while aspirin reduces the effectiveness of INH. So, aspirin should be avoided when using drug regime containing INH to prevent it from interfering with INH mechanism. (1447 words) Benefits and Risks of Drug Treatment As with all forms of medications, tuberculosis drugs also pose some side-effects which may cause uneasiness to the patient. The benefits of tuberculosis drug treatments are well known. It effectively reduces symptoms of the disease upon the administration of the medication and in most cases; the drug cures the disease with 2-3% of relapse rate. Drug treatment also decreases the mortality rate significantly; reducing it to less than 5%. This means number of people dying from tuberculosis or tuberculosis related diseases is falling every year. On the other hand, the risks of drug treatments are severe but only in remote cases. This is usually due to the aggravation of the side-effects by the risk factors such as alcohol abuse, history of hepatitis, diabetes mellitus and HIV infection. Increasing age is also a risk factor for the noncompliance to the treatment. The severe forms of side-effects are drug-induced hepatitis, arthralgia, central nervous system toxicity and exanthema. The drug treatments also pose some rather common adverse-effects. These include nausea, abdominal pain, fever, diarrhea and fluid (saliva, tears and urine) discolouration. Table1-Number of side-effects due to isoniazid, rifampin or pyrazinamide followed by final termination of  one of the drugs (n=519) Side-effect Isoniazid Rifampin Pyrazinamide Total Hepatotoxicity 19(4) 8(1.5) 28(5) 55(11) Arthralgia 1(0.2) 12(2) 13(2) Exanthema 6(1.2) 27(5) 33(6) CNS toxicity* 8(1.5) 8(1.5) Nausea 5(0.9) 5(0.9) Others# 7(1.4) 7(1.4) Total 34(7) 8(1.5) 79(15) 121(23) Values are present as absolute number, and percentage in  parenthesis. *:including peripheral neuropathy(n=6) and  seizure(n=2); #:including leucopenia(n=1), fever(n=3) and  severe hyperuricaemia(n=3). CNS: central nervous system. After evaluating both pros and cons of the drug treatment, I feel that the benefits of drug treatment outweigh the risks. Therefore, the risks should not discourage the patient from continuing the medication. The completion of the medication is vital for the full recovery from the disease. Social and Economic Implications of the Disease Tuberculosis is the worlds largest endemic with one third of world population being infected with the disease. And tuberculosis remains the greatest terror in developing nations. This is because the disease causes unbearable social and economic implications to the one infected with the disease. The substantial non-treatment costs of TB are borne by the patients and their  families. These are often greater than the costs of treatment to the health sector.   The largest indirect cost of TB for a patient is income lost by being too sick to work. Studies suggest that on average three to four months of work time are lost, resulting  in average lost potential earnings of 20% to 30% of annual household income. For the families of those that die from the disease, there is the further loss of about  15 years of income because of the premature death of the TB sufferer. Extracted from the Stop Tb Initiative by WHO It is very clear that tuberculosis, left untreated, would result in loss in terms of financial support. Therefore, it is vital for the authority to provide necessary treatment to the patients and, at the same time, they should also work on preventive measures such as awareness campaigns and vaccinations to prevent the spread of the disease. The World Health Organization (WHO) have cited TB treatment as one of the most cost-effective health interventions accessible at a cost of only $10 for every year of life gained. Effectively treating TB will not solve the worldwide AIDS crisis, but it will significantly reduce its burden Dr Piot, Executive Director, Joint United Nations Program on HIV/AIDS On the other hand, a person with tuberculosis would have to live as an outcast. This is very true in the poorer nations of the world where the people do not have enough knowledge about the disease thus exiling the patient from their community. This would result in the patient losing moral support and faith which may ultimately lead to suicide. (2093 words) Alternative Solution Ayurvedic treatment Ayurveda, traditional Indian medication, is also proven to be effective in combating against tuberculosis. Current tuberculosis drug treatments induce unfavourable side-effects such as decreased appetite and liver inflammation. On the long run, it could lead to permanent liver damage. Therefore, combined with ayuvedic medication such as Kutki (Picrorrhiza kurroa), Guduchi (Tinospora cordifolia), Sharapunkha (Tephrosia purpurea) and Kalmegh (Andrographis paniculata) would prevent any damage to the liver and would result in increased efficiency in treating the disease. Tuberculosis of the lymph glands also could cause serious problems. Ayurvedic medicines like Kancnnaar (Bauhinia variegata), Kanchnaar Guggulu and Triphala Guggulu can increase the bodys immune response towards the disease. These ayurvedic medicines when combined with correct drug regimes would effectively fight off the disease and prevent it from relapsing. Ayurvedic medicines are known to increase immune response signi ficantly, thus, making the body to be able to fight the infection. Prevention Methods Vaccination Besides drug treatments, there is another practical approach to eradicate the endemic worldwide. This solution aims at preventing the disease. Vaccination is the best, available solution for most of the contagious disease. For tuberculosis, Bacillus Calmette Guerin (BCG) is the current available vaccine. This vaccine is actually an attenuated strain of live mycobacterium bovis which has lost its virulence after being carefully cultured artificially for many years. This vaccine works by providing natural passive immunity in which the infection with bovine tuberculosis would protect against infection with human tuberculosis. This is the result of memory cells in our body being able to recognize the same type of infection and providing instant protection against the disease. BCG is found to be very effective in giving protection primarily in children aged 3 and below and teenagers aged 14-20. Efficiency of BCG also differs according to geography. The first large scale trial evaluating the efficacy of BCG was conducted from 1956 to 1963 and involved almost 60,000 school children who received BCG at the age of 14 or 15; this study showed an efficacy of 84% up to 6 years after immunization. However, a US Public Health Service trial of BCG in Georgia and Alabama published in 1966 showed an efficacy of only 14%, and did much to convince the US that it did not want to implement mass immunization with BCG. A further trial conducted in South India and published in 1979 (the Chingleput trial), showed no protective effect. Extracted from Bacillus_Calmette-Guerin_Wikipedia-the_free_encyclopedia. Reducing exposure Tuberculosis is directly dependent on the degree of exposure. The more a person comes into contact with the disease, the higher is the chance to suffer from active tuberculosis. Generally, inhalation of minute amount of the bacilli would result in the immune response which immediately inactivates the disease thus preventing it from progressing. However, a direct exposure to a relatively high amount of the bacilli would result in the immune system to be unable to wall off the disease fast enough. This would result in the person developing active tuberculosis although he may not have the history of the disease before. Therefore, visit to places with a high incidence of tuberculosis should be avoided. Furthermore, we should also avoid close contact with people infected by the disease. Apart from that, personal hygiene, and the practice of wearing mask should be cultured in the society to prevent the spread of the disease. On top of that, self-quarantine should be practiced by individual s if they are suspected to carry the infection. Evaluation For the research on this issue, I have used a number of sources ranging from websites to newspaper articles and books. The World Health Organisation official webpage; http://www.who.int/en/ is one of the sources that I have used in my research. I find that this website provides loads of information regarding tuberculosis. This source is definitely trustable as it is the official webpage of a world-recognized organization which is committed to the welfare of the people. The facts and information obtained from this website is valid and reliable under any circumstances because they are up to date. Moreover, WHO have also organized research on this issue and the findings have been reviewed by experts from all over the world. One such research is the Economic Impacts of Tuberculosis. On top of that, I found that a lot of other websites such as http://en.wikipedia.org/wiki/Tuberculosis, http://www.plospathogens.org/article/info:doi%2F10.1371%2Fjournal.ppat.1000600 and http://www.wrongdiagn osis.com/t/tuberculosis/stats.htm have cited WHO in their websites. This proves that WHO is a reliable source of information for this issue. Furthermore, I have evaluated another source http://www.mayoclinic.com/health/tuberculosis/DS00372/DSECTION=treatments-and-drugs and found that there are similarities in terms of facts presented in the website with other renowned websites such as http://en.wikipedia.org/wiki/Tuberculosis_treatment, http://familydoctor.org/online/famdocen/home/common/infections/common/bacterial/120.html, and http://www.nlm.nih.gov/medlineplus/tuberculosis.html. Similar information was also found in the journal Risk factors for side-effects of isoniazid, rifampin and pyrazinamide in patients hospitalized for pulmonary tuberculosis from the European Respiratory Journal. This source, therefore, is trustable because it has a lot of correspondence with other sources.

A Raisin in the Sun and Brown versus Board of Education :: Race Racial Segregation Lorraine Hansberry

The American Dream Langston Hughes wrote a poem, in 1951, called â€Å"Harlem†. It sums up the play A Raisin in the Sun, by Lorraine Hansberry: â€Å"What happens to a dream deferred? Does it dry up like a raisin in the sun? Or fester like a sore- and the run? Does it stink like rotten meat? Or crust and sugar over- like a syrupy sweet? Maybe it just sags like a heavy load. Or does it explode?† Lorraine Hansberry uses this poem to open A Raisin in the Sun. This dialogue suggests what happens to the African American’s dream during the Brown v. Board of Education trials. While critiquing this play I was a little disappointed that Brown v. Board of Education was not discussed directly. However, I did find the plot of the play, and the people who were attending it to be very interesting. The plot of A Raisin in the Sun does not directly talk about the Brown v. Board of Education decision. Actually, very little of the play, until the end, deals with any kind of racial segregation. The play revolves around four main characters; Walter, a defiant husband who desperately wants to become rich; Ruth, Walter’s devoted wife; Beneatha, Walters intellectual younger sister, who is much better educated than the others and wants to become a doctor; and Mama, the head of the household, and also Walter and Beneatha’s mother. Mama inherits some money from her dead husbands insurance. With this money she buys a house in an all white community, and gives the rest to Walter. He is instructed to put some money away for Beneatha’s medical school, and the rest into a checking account for himself. Walter, however, desperate to become rich foolishly gives the money to his friend to invest in a liquor store. His so called friend runs off with all of the money Walter gave him. In order to get some money back for Beneatha to go to school, Walter wants to sell the house back to the white community. The community offered the Younger family a lot of money for the house, because they did not want Negroes living next to them. In the end however, Walter, realizes that it is this house that unifies the family and is what truly will make them happy, instead of being rich.

Lab Report of the Preparation of Cds

EXPERIMENT REPORT (PREPARATION OF CdS) Experiment Purposes 1. To master the proper operations as well as the suitable situations of atmospheric pressure filtration, vacuum filtration, centrifugal separation & precipitation washing 2. To understand the relation between precipitation state % precipitating conditions 3. To learn the way to examine whether reactants are fully precipitated 4. To learn the principals of powder material synthesizing through room temperature solid phase method & liquid phase method directional growing rystal form of precipitation Experiment Principals 1. the process of precipitation forming constitutive crystal ion accumulating growing forming nuclei sediment particals amorphous precipitation crystal nuclei 2. the classification of precipitations amorphous precipitation, particle diameter smaller than 0. 02 m, ex. Fe(OH)3. the hydroxide of metals of high oxidation number would grow directionally with low rate, but accumulate very fast, forming amorphous prec ipitation curd-like precipitation, particle diameter 0. 02~0. 1 m, ex.AgCl crystal form of precipitation, diameter 0. 1~1 m, ex. BaSO4. Inorganic salts with strong polarizability grow directionally with high rate, forming crystal form of precipitation 3. CdS is a semiconductor material widely use. It can be preparated through room temperature solid phase method & liquid phase method & gas phase method. Use CdSO4 and NaS as reactants, through both room temperature solid phase method & liquid phase method to prepare CdS(s). Compare the two ways of preparation and their influence on product separation. Reactions as ollows, CdSO4+2NaS=CdS+Na2SO4 Chemical reagents: CdSO4(s), Na2S(s), 0. 3M HCL(aq), 0. 5M CdSO4(aq), 1M BaCl2(aq), widely pH tests strips, mortar, centrifugal text tube, bake oven, centrifuge, vacuum filtration apparatus, etc. Experiment Steps And Phenomena Room temperature solid phase method 1. according to the theoretically volume of product should be 1. 44g, weigh certain amount of CdSO4(s) and NaS(s), mix in dried mortal, then grind for 10-20 min. | In the mortal, White particles slowly turned into orange powders, bad egg smell is output. | 2. he product is transferred to a beaker and washed with distilled water for 3 times, until the supernatant is tested pH

Notes on Sales and Marketing

Create a Marketing Plan A good marketing plan can shape the way you connect to your existing customers and attract new ones. It can also help you determine the types of customers you should target, how to reach them and how to track the results so you learn what works to increase business. If you don't have a marketing plan, creating one is not difficult. A successful marketing plan doesn't have to be complex or lengthy, but should contain enough information to help you establish, direct and coordinate your marketing efforts.To help you through the process, we've identified five steps to follow. These encompass information gathering before you write your marketing plan, the drafting of the plan itself, and updating the plan after you've created it. Along the way we use Margie's Travel, a new 25-person travel service company, as an example. Step 1: Position your product or services To start your plan, keep in mind the four â€Å"Ps† of marketing: product, price, promotion and p lace. Your goal is to put the right product or service in front of the right customers, at the right price and at the right time and place.A good way to get started is to answer some basic questions about your business. The following scenario for Step 1 is based on the marketing plan used by Margie's Travel. †¢| Who are you selling to? Margie's Travel provides personal travel services to busy working professionals. Based on collected data, the typical clients are homeowners between the ages of 35 and 55, with yearly incomes of more than US$100,000. | †¢| What do those customers need? The target market for Margie's Travel is affluent working couples with children who want travel plans customised for a family.The company's goal is to provide convenient, unique and relaxing travel experiences appropriate to each family. | †¢| What distinguishes your product or service from the competition? Margie's Travel has a competitive advantage in its ability to accommodate families with children of all ages, from putting together fun and entertaining travel packages to making special accommodation travel plans with short or extended notice, flying domestically or internationally. Margie's Travel also has the advantage of being a home-based business that equires lower overhead and start-up costs than a traditional travel service business. | †¢| Are there marketing tactics that work best for your business? Research indicates that the most effective advertising tool for a service like Margie's Travel is small display ads in local papers, such as a weekly community newspaper with a paid subscription base of 5,000 to 40,000 readers. Margie's Travel also places ads in the local boating community newsletter, and sends brochures to larger businesses. By answering these key questions about your business, you can develop a solid foundation on which to build your marketing plan. Step 2: Ask for input from trusted advisors To ensure that you have a clear sense of yo ur own business, it is a valuable practise to gather information from those around you. Set up meetings with trusted friends, staff, advisors and peers, and ask for their input on the following: †¢| Who is your business selling to? | †¢| What do your customers need? | †¢| What distinguishes your products or services from the competition? | †¢| When and how often should you employ marketing efforts? †¢| Where should your company be one year from now? | Getting feedback on these aspects of your business can help you prepare your marketing strategy as well as create targeted materials. Step 3: Ask for input from customers and prospective customers To successfully market to customers, you need to learn how they react to your product, pricing, brand or service — anything related to your business. Ask several of your current and prospective customers what they think about your business, products and services, potential to sell to them, and competitors.You c an ask them by e-mail, telephone or marketing postcards. Incentives, such as discounts or samples, can encourage feedback. Step 4: Draft your plan Now that you have feedback and an outline, you can draft your marketing plan. Start by summarising your market position and goals, and define what you expect to accomplish in a specific time period. A typical marketing plan might be organised in the following way: †¢| Market Summary| †¢| Competitive Landscape| †¢| Product Comparison and Positioning| †¢| Communication Strategies| †¢| Launch Strategies| | Packaging and Fulfillment| †¢| Success Metrics| †¢| Marketing Schedule| With a marketing plan in place, you have a structure you can use to help keep your business on track. Step 5: Track your results, update your plan Reviewing your plan every six months helps you determine whether it is producing the results you need. You can easily track your progress with a spreadsheet, where you can also calculate yo ur marketing costs and compare them with sales and other metrics. You should also update your plan regularly to respond to changing market